This volume covers data describing the role of free radicals and antioxidants that deal with clinical and pre-clinical trials, as well as basic research in the area of women's health. There is increasing evidence that oxidative stress is a causative, or at least a supporting factor in female pathology and infertility. During advancing gestational age, oxidative stress biomakers rise. Oxidative stress plays a regulatory role in transcription, signal transduction, gene expression and membrane trafficking. A search on Pub Med shows 449 papers have been published to date related to women's health disorders and use of antioxidants in a variety of disease that are prevalent in women, such as hypertension and cardiovascular disease, osteoporosis, obesity and restless leg syndrome.
Oxidative stress in women's health has been of interest only in the last two decades. The gap between the basic research and the clinical practice has been the main reason for the lack of progress. As in many areas of medicine, research is ahead of the clinical practice. This book aims to bridge this wide gap, promoting scientific curiosity and laying the foundation for evidence-based practice. Written by leading experts on reproductive health and fertility, the Studies on Women's Health is of great interest to infertility specialists, gynecologists and reproductive endocrinologists. This volume also addresses the complex interplay of oxidative stress in cardiovascular disease and relationship with women's health.
The book covers over its seventeen chapters almost every aspect in female reproduction. Oxidative stress effects oogenesis, folliculogenesis and embryogenesis. The role of oxidative stress in pregnancy maintenance and loss is of prime importance. Premature rupture of membranes is a challenge to all practicing obstetricians. Studies on Women's Health covers polycystic ovarian syndrome, endometriosis which are the two most common diseases in women of reproductive age. The role of oxidative stress in assisted reproduction is elegantly discussed in this book.
Oxidative stress in women's health is written by leaders in reproductive medicine. Ashok Agarwal is Professor of Urology, Cleveland Clinic, Ohio, USA; Botros Rizk, Professor of Obstetrics and Gynecology, University of South Alabama College of Medicine, Mobile, Alabama, USA; Nabil Aziz is a consultant gynecologist, Liverpool University, Liverpool, England.
From the reviews:
"This book is an excellent and informative addition in the field of oxidative stress and antioxidants in relation to all aspects of women's health, and it is easily accessible to a wide audience. Each chapter is clearly written with extensive diagrams to further illustrate the text. ? this book will prove useful for postgraduate students and others new to the field. ? it is a well sourced and well constructed textbook that will stand the test of time." (Hiten D. Mistry, The Obstetrician & Gynaecologist, Vol. 15, 2013)
