In this fourth book in the New York Times bestselling series, Frank Einstein (kid-genius scientist and inventor) and his best friend, Watson, along with Klink (a self-assembled artificial intelligence entity) and Klank (a mostly self-assembled and artificial almost intelligence entity), once again find themselves in competition with T. Edison, their classmate and archrival-this time in a quest to unlock the power behind the science of life with Frank's newest invention the EvoBelt, which allows the user to evolve into other forms of life.

Boy genius Frank Einstein finds himself in competition with his classmate and archrival T. Edison and his sign-language-speaking sidekick, Mr. Chimp, over Frank's newest invention: the EvoBlaster Belt.