Malaria is a chronic infectious disease caused by single-celled microorganisms belonging to the Plasmodium group. It can be caused by five species of Plasmodium, namely, P. falciparum, P. vivax, P. malariae, P. ovale, and P. knowlesi. However, it is most commonly caused by P. falciparum. Its common symptoms include headache, tiredness, vomiting and fever. The microscopic examination of blood by using blood films is the most common diagnostic method. Other diagnostic tests include malaria antigen detection tests and microscopy. Treatment methods include the intake of artemisinin, lumefantrine, mefloquine and sulfadoxine/pyrimethamine. This book will also provide interesting topics for research, which interested readers can take up. It strives to provide a fair idea about malaria and to help develop a better understanding of the latest advances within the field of malaria research. This book includes contributions of experts and researchers, which will provide innovative insights into this disease.